SYMPATHETIC VASODILATATION IN THE RABBIT EAR
نویسندگان
چکیده
منابع مشابه
Functional and structural changes in the rabbit ear artery after sympathetic denervation.
We studied the tissue weight, dimensions, contractility, elasticity, and sensitivity to exogenous norepinephrine (NE) of denervated and innervated segments of the central ear arteries of white New Zealand rabbits. Three different age groups received unilateral superior cervical ganglionectomies, "growing" at 3-4 weeks, "young adult" at 9-11 weeks, and "mature" at 16-20 weeks. In the growing gro...
متن کاملEffect of sympathetic denervation on smooth muscle cell proliferation in the growing rabbit ear artery.
The effect of sympathetic denervation on the uptake of 3H-thymidine (3H-Tdr) into the ear artery of a growing rabbit was studied in vitro and in vivo. Uptake into the right artery was compared with that into the left 2 and 3 weeks after left superior cervical ganglionectomy in 4-week-old rabbits. Denervation was confirmed by the absence of catecholamine fluorescence. The total uptake of 3H--Tdr...
متن کاملEffects of Hypertension and Hypercholesterolemia on Vasodilatation in the Rabbit
Vasodilator substances act either directly on vascular smooth muscle (e.g., adenosine) or indirectly (e.g., acetylcholine) on endothelial cells that respond by releasing an unknown powerful, short-lived relaxing factor. To determine whether chronic hypertension or hypercholesterolemia or both would alter the release of the endothelium-derived relaxing factor, experiments were performed in hyper...
متن کاملComparison of constrictor responses of the rabbit ear artery to norepinephrine and to sympathetic nerve stimulation.
The perfused isolated rabbit ear artery was used as a vascular model to compare the constrictor responses to exogenous and endogenous norepinephrine. The aim of the study was to estimate the concentrations of norepinephrine reaching the smooth muscle of the artery during sympathetic nerve stimulation. The artery was perfused so that exogenous norepinephrine was introduced exclusively from the a...
متن کاملComparison of Constrictor Responses of the Rabbit Ear Artery to Noreplnephrine and to Sympathetic Nerve Stimulation
The perfused isolated rabbit ear artery was used as a vascular model to compare the constrictor responses to exogenous and endogenous norepinephrine. The aim of the study was to estimate the concentrations of norepinephrine reaching the smooth muscle of the artery during sympathetic nerve stimulation. The artery was perfused so that exogenous norepinephrine was introduced exclusively from the a...
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ژورنال
عنوان ژورنال: British Journal of Pharmacology and Chemotherapy
سال: 1962
ISSN: 0366-0826
DOI: 10.1111/j.1476-5381.1962.tb01457.x